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Microscopic analysis of the calcified masses based on their collagen fibre orientation in peripheral ossifying fibroma by Dr DC Shetty
Peripheral Ossifying Fibroma is a reactive lesion exhibiting a diverse spectrum of the histopathology that accounts for the 9.6% of the gingival lesions. A research is being done on “A polarising microscopic analysis of the calcified masses based on their collagen fibre orientation in peripheral ossifying fibroma” by Dr Devicharan Shetty, Aadithya B Urs, Puneet Ahuja, Harish C Rai, Seema Sikka, Anschutz Sahu and Yuhina Sirohi. All the authors except Puneet Ahuja are from Department of Oral and Maxillofacial Pathology and Microbiology, ITS-CDSR, Muradnagar, Ghaziabad, Uttar Pradesh, India and Puneet Ahuja is from ITS Dental College, Greater Noida, Uttar Pradesh, India.
Gingiva is the prominent, easily accessible and commonly offended part of the oral cavity and it has been clinically involved in the presentation of various pathological lessons and as well as conditions. The reactive lesions are divided due to their occurrence and one of them is Peripheral Ossifying Fibroma.
The study provides a detailed clinical, radiographic and histopathological analysis of the 15 cases of POF (Peripheral Ossifying Fibroma) retrieved from the departmental archives. The cases were subsequently stained with the histochemical stain and it was observed under the polarising microscope. This particular study is an effort to understand and analyse the diverse spectrum of the mineralized components and also all their surrounding tissues. Clinically, the study also revealed a female predilection (73%) with second and the third decade commonly affected. The common site was the interdental papilla of the anterior region, that presents itself pink and sessile nodular mass.
The radiographic examination done revealed 93 % cases that show o manifestation on the radiograph.
Histopathological analysis was done in research by Dr DC Shetty and other members showed 73% cases that exhibited a fibro-cellular connective tissue stroma with the plump fibroblasts around mineralized areas and much other analysis were done.
The studies were done and carried out so far with the help of the microscope to decipher presence of kind of the mineralised tissue gave rise to the findings of the definitive presence of the cementum, bone as well as the combination of both. The presence of tissue architecture and also the type of cell emphasises that these growths are metaplastic in origin but they arise de novo. This would also lead to the analysis that may also suggest the origin of lessons in deeper structures that in the close association with the tooth. And there are further more studies are required to relate all the clear association between undifferentiated cells of the PDL that gives rise to the POF so that to emphatically hypothesise of the present findings. The research work done by Dr Shetty and others is so valuable.