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albecker   , 36

from Scarsdale



Trintellix is a brand name which uses the drug Vortioxetine. It is an antidepressant medication.

What is Prozac?

Prozac is a brand name which uses the drug Fluoxetine. It is an antiderpessant medication.

Difference between Trintellix and Prozac?

Vortioxetine is a SSRI ( Selective Serotonin Reputake Inhibitor) and Serotonine Modulator.. Fluoxetine is a SNRI ( Selective Serotonin Norepinephrine Reputake Inhibitor).

Side effects of Trintellix?

a) Vomitingb) Constipationc) Nausead) Dizzinesse) Decrease in sexual ability and interest Serious side effects that require medical help and supervision-
a) Shakingb) Restlessnessc) Inability to concentrated) Change in Memorye) Lack of concentrationf) Confusion g) Fast heartbeath) Hallucinations

Side effects of Prozac?

a) Nauseab) Dizzinesse) Loss of appetited) Loss of sleepe) Drowsinessf) Tirednessg) Sweating Serious side effects that require medical help and supervision-
a) Severe mood changes like suicidal thoughts, anxiety, unusual high energy or excitement levels, anxiety.b) Rapid weight lossc) Easy bruisingd) Muscle weaknesse) Decreased interest in sex f) Vision changeg) Black stoolsh) Seizures

Form of Trintellix

It is an oral tablet. It comes as a 5 mg, 10 mg and 20 mg tablet each of pink, yellow and red color respectively.The letters "TL" are engraved on one side and the quantity ( 5,10,20 ) is engraved on the other

Form of Prozac

It is for oral consumption and is in form of a capsule or liquid. Depending on the quantity used (10 mg, 20 mg) it comes in different colors ( green for 10 mg, green and yellow combination for 20 mg ).

Interaction of Trintellix with other drugs

Inform your doctor about other medications being used by you or if you are likely to use them in future -
a) Aspirin

b) MAO ( Monoanime oxidase ) inhibitors

c) Antiplatelet drugs

d) Any drug that increases serotonin in the body

e) Other antidepressants
Interaction of Prozac with other drugs
Inform your doctor about other medications being used by you or if you are likely to use them in future -
a) Tricyclic antidepressants

b) Antiplatelet drugs

c) MAO ( Monoanime oxidase ) inhibitors

d) Allergy medicines

e) Narcotics

f) Muscle relaxers

g) Seizure medicines

This is generic information. Please consult your doctor for detailed and specific information on which drug combinations to use or avoid.

Dosage instructions for Trintellix

Take about 10 mg tablet daily for adults below 65 years. 5 gm for adults above 65 or as prescribed by the doctor. Do not take beyond 20 mg per day. Can be taken with or without food.

Dosage instructions for Prozac

Take it only according to the prescription.

Do not break or chew the capsule. Swallow it whole. If it is in liquid form measure carefully the exact amount prescribed with a measuring cup. Can be taken with or without food.

Overdose or Missed dosage

In case of overdose contact a medical practitioner or some other concerned authority.

In case of missed dosage, take it immediately when you recall having missed the dose and if the time for next dose is really close (half-an-hour to four hours) then skip the current dose and follow the regular schedule. Do not take two doses at the same time.


Keep in a cool, dark place away from sunlight and moisture. Keep it away from kids and pets.

How to Take Ciprofloxacin to Prevent Anthrax


Anthrax is a rare but serious medical condition which can be fatal. It’s usually caused by Bacillus anthracis, a bacterium that forms spores. A person can contract it by coming into contact with anthrax germs.

Symptoms of Anthrax

This condition normally manifests itself under four different forms. This means that the symptoms vary depending on the form of anthrax infection.

•Cutaneous Anthrax normally enters the human body via sores or cuts on the skin. It displays symptoms such as an itchy bump with a black center. Besides that, a patient may end up with swelled lymph glands. •Pulmonary Anthrax develops after you breathe air that contains the anthrax germs. The patient may display flu-like symptoms such as fatigue, muscle aches, mild fever, and sore throat.

•Gastrointestinal Anthrax is an infection that’s caused after ingesting undercooked meat from animals that had anthrax. Symptoms include fever, headaches, vomiting, nausea, and loss of appetite.

•Injection Anthrax is usually contracted by injecting yourself with illegal drugs. Although it’s very rare, several cases have been reported in the past few years. Symptoms of Injection Anthrax include significant swelling and redness in the injection area.

Ciprofloxacin and Anthrax

Cipro is one of the antibiotics that’s used to treat Anthrax. The FDA approved prescription drug is a powerful antibiotic that is effective in treating bacterial diseases such as anthrax.

How Ciprofloxacin should be taken

Adults and children who weigh 31 kilograms or more should take one pill in the morning and another pill in the evening. Each pill should be taken with a full glass of water, with or without food. Children who weigh less than 31 kilograms will have a customized dose depending on their weight.

Note: ciprofloxacin should be taken as per the doctor’s instructions to avoid unwanted side effects.

Who Shouldn’t Take Ciprofloxacin?

As much as this antibiotic is effective in treating Anthrax infections, it’s not advisable to take it if you are allergic to medications that belong to the quinolones group. An allergic person may end with a severe reaction that includes swollen lips, face, or tongue. Besides that, some people may end up experiencing trouble breathing. If you have had myasthenia gravis in the past, then you should also avoid taking this drug.


This antibiotic should not be taken if you are taking a drug such as Zanaflex. Additionally, you need to speak to your doctor if you are taking drugs for diseases such as schizophrenia, diabetes, and asthma. Do not skip any dose and in case you miss a dose by mistake, simply wait until the next scheduled time. Avoid taking two doses at once. Ciprofloxacin should not be crushed or split. Swallow it with water only and not yogurt, milk, or juice.

Possible Side Effects of Ciprofloxacin

The side effects of ciprofloxacin are usually mild and they include sunburns, vomiting, and vaginal yeast infection. However, some people may end up experiencing serious side effects such as:

•Breathing problems

•Dizziness, seizures, or tremors

•Skin rash including wheals and hives

•Serious stomach cramps and diarrhea

•Dark brown urine

In case you end up with serious side effects, seek professional help as soon as you can. Even though ciprofloxacin antibiotic can result in mild or serious side effects, its benefits outweigh the downsides, especially if you are using it to treat a serious medical condition such as anthrax.

What is Provigil?


Provigil, also available in its generic form (modafinil) is a popular prescription medication provided to treat excessive sleepiness symptoms caused by obstructive sleep apnea (OSA), narcolepsy and shift work Provigil is a schedule IV prescription drug which means it is one of the controlled substances. It can be abused and may also cause dependence. However, Provigil does a great job at helping users stay awake and is the first choice prescription for the above conditions.

Provigil uses

As aforesaid. Provigil is provided for those struggling with staying awake. The FDA approved usage is for encouraging daytime wakefulness in patients suffering one of the following;

Obstructive sleep apnea (OSA)


Shift work sleepiness

Provigil is also sometimes used as the second or third choice for non-approved uses such as;

  • ADHD
  • Depression
  • Multiple sclerosis
  • Anxiety
  • Weight loss

However using Provigil for these non-approved uses is highly discouraged as it may easily lead to dependence and abuse.


Provigil comes in two measures; 100mg, 200mg. The dosage prescribed will depend on various factors including age, severity of the condition (sleepiness), pre-existing medical conditions and counteractions. It is important to notify your doctor about any condition or other drugs you are currently using. Typically, you will be started on a lower dosage which will be adjusted until your right dose is reached. The basic low and high dosage is as follows;

Narcolepsy and sleep apnea - 200mg once a day to 400 mg once a day in the morning

Shift work - 200mg once a day an hour before the shift begins

Patients with liver problems - 100mg once a day

Seniors - 100mg or lower. Follow the doctor's prescription

If you miss your dose, take it the moment you remember unless it is close to your bedtime. Provigil will keep you awake for several hours so it should not be used if you are planning to go to bed soon. It can be taken with or without food. Never take two doses at a time to compensate for forgotten doses. Do not crush or split the tablet.


Provigil interacts

differently with certain medication, supplements and even food. The interaction may interfere with how well the drug works, how other drugs and substances work or the side effects. Avoid taking Provigil if you are already using the following medication;

a) Antiviral drugs - Cobicistat (Tybost), Viekira XR, Viekira Pak, Darunavir (Prezista) and Ritonavir (Norvir)

b) Antifungal drugs - Itraconazole (Onmel, Sporanox), Flucanozole (Diflucan), etoconazole

c) Antibiotic drugs - Erythromycin (Ery-Tab, E.E.S, Erythrocin), Clarithryomycin (Biaxin)

d) Heart medications - Dilitiazem (Cardizem, Taztia XT, Cartia XT, Tiazac), Amiodarone (Nexterone, Pacerone) and Verapamil (Verelan, Calan)

Other drugs to watch for include oral contraceptives, phenytoin, warfarin, midazolam, cyclosporine, triazolam, clomipramine, omeprazole, diazepam, propranolol and MOAIs (monoamine oxidase inhibitors) among others.

Foods and supplements that may cause interaction include acacia rigidula, caffeine (coffee, chocolate, soda and tea), bitter orange, hordenine, guarana, fruit juices and Indian snakeroot. It is also advisable to avoid alcohol and marijuana smoking.

Side effects

The side effects of Provigil range from mild to worse. If you are experiencing any strange feeling or side effect after using Provigil, contact your doctor. Some of the common side effects include headache, nausea, anxiety and nervousness, loss of sleep and appetite, dry mouth, runny nose, diarrhea, stomach upset, back and chest pain and dizziness.

Less common side effects include rapid heartbeat, constipation, depression, tremor, vertigo and confusion. Severe side effects may range from serious rash and allergic reactions to heart problems, mental health issues, dependency and delusions.


While Provigil is a stimulant, its mechanism of action is different from others that stimulate the central nervous system. Provigil has been shown to significantly improve wakefulness in patients of the abovementioned conditions. However, the prescription should be strictly monitored and taken as advised by the doctor. This will reduce the chances of dependency, abuse and severe side effects. More importantly, purchase the approved prescription from reputable licensed and accredited drug suppliers.

What You Need To Know About Entyvio


Entyvio is a form of prescribed medication used to treat Inflammatory bowel disease(IBD). It contains a drug known as Vedolizumab. Its grouped under Integrin receptors antagonists and works by binding itself on the integrin in the body so as to stop any inflammation or in the digestive tract. The drug is mostly used to cure Crohn's disease or Ulcerative Colitis in people with moderate to severe symptoms. It is mostly recommended for people who have not had any significant improvements from other forms of medications.

How it is Taken

Before taking Vedolizumab its important to be up to date with your vaccinations and also read the medication guide provided. The drug is given through intravenous (IV) infusion. The injection through the vein should be slow and should take at least thirty minutes. The drug is taken in stages, that is, the first dose given at the time of treatment, then the second dose is given after two weeks and the third taken four weeks later after the second dose. Depending on your doctor's advice, medication continues but most physicians prefer giving the patient a dose after every eight weeks.

In case one misses their appointment it is important to reschedule so as to receive your treatment. Entyvio can be used for long term treatment.

Side Effects

Entyvio has some slight to even more serious side effects. The slight side effects are:

Back pain, flu, running nose, sore throat, headache, joint pain, nausea, fever, fatigue, and cough among others.

The more serious side effects brought about by the drug are:

Infections - some of the infections brought about are cold or flu. More serious infections such as tuberculosis or even progressive multifocal leukoencephalopathy(brain infection) may occur.

Liver damage - some patients undertaking the drug may experience symptoms such as fatigue, yellowing of the white part of eyes or skin and even stomach pain which may be an indicator of liver damage.

Allergic reactions - this differs from one patient to another as it can be both severe or not. The drug may stir some allergic reactions symptoms such as flushing, rashes, and even itchy skin.

In case of severe infections, it is important to notify the doctor so as to either stop the medication or offer an alternative.

Who should take Entyvio

The drug is mostly prescribed to patients who are experiencing severe symptoms of Inflammatory bowel disease. Though it can treat both diseases it is not suitable for:

Breastfeeding Mothers Pregnant ladies

Patients with various infections Patients with allergic reactions People with liver diseases.

People undertaking other medications.

Entyvio Interactions

Entyvio can interact with other forms of medications. Before taking it be sure to consult with your doctor about other forms of medication that you are taking. Each drug taken together with entyvio may have significant side effects or even interfere with how well the drug works. Some of these drugs are a live vaccine such as measles, yellow fever, chicken pox vaccines among others, Tysabri, Tumor necrosis factor inhibitors such as Humira, Cimzia among others.

It cannot be taken together with alcohol as it might worsen your condition and bring about severe symptoms such as nausea, vomiting, diarrhea, and stomach or Intestinal bleeding.

What Need to Know About Otezla


Otezla, which is the brand name for Apremilast, is an oral treatment for Psoriatic arthritis and Psoriasis. It was officially approved on march 21,2014 to cure Psoriatic arthrities by food and drug administration. This treatment is known to prevent the action of enzyme phosphodiesterase-4.among other arthritis treatments, Otezla is the only treatment that has been approved by food and drug administration to cure Psoriatic arthritis. Apart from treating Psoriatic arthritis, Apremilast is known for the treatment of plaque Psoriasi which is a skin condition. Apremilast decreases skin swelling and increases limberness to the weak joints. In the treatment of skin conditions, it helps in lessening and diminishing redness, scaling and thickening of the skin. This treatment of skin condition was approved on September 23,2014 by food and drug administration as a supplementary medicine to be used by patients with moderate to severe conditions.


Otezla is orally taken in presence or absence of food usually two times per day or as per the doctors instructions. Don't crush, split or chew this medicine but take it whole. Dosage on how to take depends on how severe your condition is and the reaction experience after treatment. Every drug has adverse effects when taken, nevertheless if you need to turn down the side effects to this medicine , you may start by taking small doses and proceed to large doses latest. This will be according to your doctors instructions. Make sure you comply with the guidelines given.The medicine works best when taken regularly with no skips.If no improvement noticed, or if the condition aggravates, let this be known to your doctor immediately.

Associated side effects

Side effects accompanied by use of Otezla include; headache, diarrhea and nausea, these are the common effects that have been announced recently.

Complications and precautions to be considered when using Otezla

With longer usage of Otezla, various adverse effects and warnings are experienced. Loss of weights to many patients occurred during the clinical test of this medicine.Hence when using this medicine be attentive to any weight loss observed and stop using the medicine to seek for consultation. Apremilast is connected to high chances of depression. Otezla should not be taken with other medicines that cause action on enzymes as there might be reaction between them. Such medicines include rifampins, phenolbarbital, and phenytoin. Combination of these medicines reduces the successful and potency of Apremilast.

Pregnant women should use Otezla only if the medicine does not affect the growing fetus, well researched studies have not been conducted regarding this matter. Nursing women should also be careful since no study shows how Otezla affects the breast milk.An approval will be done by food and drug administration to pregnant women and treat them with Apremilast to find out any adverse effect on the matter.

Performance of Otezla during medical examination

1,493 patients with active Apremilast were examined to detect the success and protection of using Otezla. This was performed using three clinical examinations. Patients were administered combination of Otezla and placebo, they were later given Corticosteroids of low dosage. During the last trial, they were given ACR20 and results were analyzed.The integration of the treatments showed large betterment in signs and symptoms of Psoriatic arthritis.

Cost of Apremilast

Celgene manufacturers sell it at $22,500 at a wholesale per year.